Two sample MR report
C19orf60_Monocyte (Mono) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 0.0460934 | 0.5453980 | 0.9379722 |
| Weighted median | 5 | 0.0555644 | 0.0214095 | 0.0094504 |
| Inverse variance weighted | 5 | 0.0549774 | 0.0172109 | 0.0014015 |
| Simple mode | 5 | 0.0573313 | 0.0274835 | 0.1053022 |
| Weighted mode | 5 | 0.0573313 | 0.0264990 | 0.0965069 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0880264 | 3 | 0.9932345 |
| Inverse variance weighted | 0.0882920 | 4 | 0.9990538 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0039282 | 0.2410375 | 0.9880206 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 8.52e-05 | 0 | TRUE | 0.382001 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
